Date: 2024-07-13
Take a look at data extracted from previous trials and longitudinal
studies
- Hammitt et al.2022: MELODY (Phase III)
- Simões et al. 2023: phase IIb + phase III
- Ares-Gómez et al. 2024: longitudinal study in Spain
Use data from previous trials as priors to do VE
estimation
Comparing:
* Original trial estimates; * Adjusted VE estimated from current
case-control study (uninformative priors); * Adjusted VE estimated from
current case-control study (trial data as informative priors)
Medically attended RSV LRTI (Hammitt et al)
- extracted from case-control: RSV+ LRTI as cases vs. RSV- LRTI as
controls


Medically attended all-cause LRTI (Hammitt et al)
- extracted from case-control: records with LRTI symptoms as cases
vs. those without LRTI symptoms as controls


Compare the results
